Faculty and Staff

• Phytochemical Chemoprevention
• Apoptosis & Caspase Signaling
• Chemo/Radio-Resistance Reversal
• PI3K/Akt and other Serine Threonine Kinases (Aurora Kinases) Signaling & EMT
• Altered telomerase and mitochondrial dynamics in cancer
• Metabolic Reprogramming in Cancer

Ongoing Projects:

• PI: Unraveling the Potential Therapeutic Impact of Biguanide Derivatives on EGFR/HER2-enriched Breast Cancer with a Special Emphasis on TERT-mediated Mitochondrial Dynamics (CSIR-ASPIRE, 2024–Present).
• PI: Assessment of Plasticity of Glutamine Metabolism to Determine Cisplatin Therapy Response in Cervical Cancer Cohorts of Eastern and North-Eastern India (DHR, Govt of India, 2023–Present).
• PI: Crosstalk between Glucocorticoid Receptor and Stemness Factors in Breast Cancer (CNCI Intramural, 2021–2024).

Notable Completed Projects:

• PI: Modulation of therapeutic targets Aurora kinases A and B by phytochemicals in breast cancer cells (DST, 2015–2019).
• PI: Role of natural histone deacetylase inhibitors towards sensitization of tumor cells (DST SERC Fast Track, 2008–2011).

Publications & Scholarly Impact

• Total Publications: 57.
• Cumulative Impact Factor: 94.944.

• Aurora Kinase A inhibitor alisertib failed to exert its efficacy on TNBC cells due to consequential enrichment of polyploid giant cancer cells (PGCCs), Discover Oncology, 16, 2043 (2025). https://doi.org/10.1007/s12672-025-03825-0
• Polysaccharide Extract of Ganoderma resinaceum Restricts Breast Cancer Progression..., Rev. Bras. Farmacogn. 35, 1404–1424 (2025). https://doi.org/10.1007/s43450-025-00702-3
• Glucocorticoid Receptor Interacts with B-cell Lymphoma 2 for Domineering Aggressiveness of Breast Cancer, Journal of Current Oncological Trends, 2024.
• Restoration of radiosensitivity by Genistein, a soya isoflavone is accomplished by facilitating DNA damage response in radio-resistant cervical cancer in vitro. Journal of Radiation and Cancer Research; 15(4):p 200-210, Oct–Dec 2024.
• Glucocorticoid receptor: a harmonizer of cellular plasticity in breast cancer—directs the road towards therapy resistance, metastatic progression and recurrence. Cancer Metastasis Rev 43, 481–499 (2024). https://doi.org/10.1007/s10555-023-10163-6
• Refashioning of the drug-properties of fluoroquinolone through the synthesis of a levofloxacin-imidazole cobalt (II) complex and its interaction studies on with DNA and BSA biopolymers, antimicrobial and cytotoxic studies on breast cancer cell lines. International journal of biological macromolecules, 253(Pt 8), 127636 (2023). https://doi.org/10.1016/j.ijbiomac.2023.127636.
• Black tea extract prevents inorganic arsenic induced uncontrolled proliferation, epithelial to mesenchymal transition and induction of metastatic properties in HaCaT keratinocytes - an in vitro study. Toxicology in vitro: an international journal published in association with BIBRA, 85, 105478 (2022). https://doi.org/10.1016/j.tiv.2022.105478
• Aspirin Restores Radiosensitivity in Cervical Cancer Cells by Inducing Mitotic Catastrophe through Downregulating G2/M Effectors. Asian Pac J Cancer Prev. 2022 Nov 1;23(11):3801-3813.  10.31557/APJCP.2022.23.11.3801
• Synthesis of Cu(II)-Caffeine Complex as potential therapeutic Agent: Studies on Antioxidant, anticancer and pharmacological activities. J Mol Liquids Volume 364, 15 October 2022, 119897.
• Phenethylisothiocyanate Potentiates Platinum Therapy by Reversing Cisplatin Resistance in Cervical Cancer. Frontiers in Pharmacology (2022), 13, 803114. https://doi.org/10.3389/fphar.2022.803114

• Young Scientist Award: Indian Science Congress, 2005.
• Reviewer: iScience (Cell Press), Scientific Reports, Frontiers in Oncology, Molecular Cellular Biochemistry, BMC Cancer, Cancer Cell International
• Memberships: Indian Association for Cancer Research (IACR), Society for Biological Chemists (SBC), and Environmental Mutagen Society of India (EMSI), Japanese Cancer Association (Annual Member)