Dr. Biswarup Basu Senior Scientific Officer-II
Department: Cancer Research
Education
Biswarup Basu (M.Sc, Ph.D)
Tel. 91-33-24765101(ext-324)
Email id: biswarup.basu@gmail.com ; biswarupbasu@cnci.ac.in
Linkedin: www.linkedin.com/in/BBasuCNCI
Google Scholar: https://scholar.google.com/citations?user=cIH-rYAAAAAJ&hl=en
Education:
Ph.D
(Life Sciences & Biotechnology),Jadavpur University
M.Sc (Zoology), University
of Calcutta, India
B.Sc (Zoology)
,University of Calcutta, India
Awards and Honors
1. NET (CSIR-JRF), June 2004,
2. NET (L.S) December 2003
3. GATE 2004(92.88 percentile),
4. SLET 2004
5. CSIR-NEHRU postdoctotorate fellowship, 2010
6. NIH (US) Postdoctorate fellowship ,2011
7. DST-Young Scientist Scheme recipient, 2015
8. DBT-IndiaBiosciences Young Investigators’ Meeting Grant recipient 2023-2024
9. DHR-HRD “Short Term Visiting Fellow in Indian Institutes” awardee 2024
10. Awarded PI projects from DBT, ICMR , WB-DSTBT and CO-PI projects from ICMR,SERB
11. Peer reviewer of Springer-Nature/Elsevier/Wiley journals and funding agencies
10. Life Member of Indian Association for Cancer Research, Indian Science Congress Association, Zoological Society of India, Indian Academy of Neurosciences
Professional Experiences
Chittaranjan National Cancer Institute, Kolkata (SSO-II) 2018- Present
Amity University Uttar Pradesh, Noida (Assistant Professor-III) 2015- 2018
Apeejay Stya University, Haryana (Assistant Professor-II) 2013- 2015
National Cancer Institute,Frederick(NIH),USA ( Postdoc visiting fellow) 2011-2013
Areas of Interest
1. Evaluation of autophagy in regulating breast cancer progression
2. Deciphering genomic markers in diagnosis and prognosis of breast and ovarian tumors
3. Mitigation of ovarian patients’ post chemotherapy neurocognitive dysfunction and neuropathy
4. Theranostic drug delivery across blood brain barrier & targeting of brain tumors
5. Development of AI based tools for pathology and radiology guidance
6. Development of bioinspired material based strategies for surgical wound healing and
chemoradiation impaired skin & bone tissue regeneration
7. Identification of microbial-neuroendocrine-immune axis associated with gastrointestinal cancer
Publications and Patents
Full publication link in Google Scholar: https://scholar.google.com/citations?user=cIH-rYAAAAAJ&hl=en
Original Articles - [*
Corresponding Author , IF=Impact Factor]
1. Ultrasound-Mediated Nanocarrier-Based Drug Delivery
in Breast Cancer Therapy. Sengupta,
S.,
Bhattacharjee, A., Basu, B., Kar, S. and Moulik, S. J Ultrasound Med,2025,45:
735-752 (IF 1.9)
2. Design, development, and evaluation of magnetic
nanoparticles and docetaxel-loaded nanosystem for brain targeting. Gandhi, H.,
Kumar, D., Ghosh, S., Basu, B., & Kapoor, D. N. Therapeutic Delivery,
2025, 16(9), 819–834 (IF 2.2)
3. Evaluation of anticancer potential of diorganotin(IV) complexes
derived from 4-nitro-3-methylbenzhydrazide: Synthesis, spectral and single
crystal analysis. Poonia S , Asija S , Lal K,
Deswal Y , Kumar D , Jindal D, Ghosh
S , Basu B et al. Journal of Molecular Structure . 2025,1338, 142361
(IF 3.1)
4. Design, synthesis, anti-breast
cancer and in silico studies of substituted triphenyl
imidazole-N-alkyl linked indole derivatives Kumar, A., Sengupta, S., Yadav, A. K., Singh, R.
P., Sinha, T., Bhattacharjee, P. et al. Future Medicinal Chemistry. 2025,17(14),
1675–1692 (IF 4.76)
5. Attenuation of c-Myc expression in breast cancer
by hesperidin-mediated stabilization of its promoter proximal G quadruplex
region. Choudhury SD, Ghosh S, Kumar P, Bhardwaj A, Singh K, Singh A, Kumar A, Basu
B, Giri R, Choudhury D. Int J Biol Macromol. 2025 May;309(Pt
4):143000. (IF 7.7)
6. Anti-proliferative and Apoptotic Efficacy of
Nano-PLGA encapsulated Quercetin Molecules by down- regulation of Akt in K-ras
mutated NSCLC cell lines, A549 and H460. Mukherjee A, Ghosh S, Ganguli S, Basu
B. J Biochem Mol Toxicol. 2025 Apr;39(4):e70240. (IF 3.9)
7. Editorial: Obesity and cancer: the possible
molecular links. Basu B*, Chakroborty D, Sarkar C. Front Cell Dev
Biol. 2025 Feb 11;13:1542429 (IF 4.5)
8. Epidermal Growth Factor Receptor (EGFR) and
SMAD4 negatively correlated in the progression of gallbladder cancer in Eastern
Indian patients. Choudhury S, Ghosh S, Chakraborty P, Pal S, Ghosh K, Saha S,
Midha J, Sankar V, Mohata A, Chattopadhyay BK, Ghosh S, Das S, Basu B,
Sikdar N. BMC Gastroenterol. 2024 Dec 3;24(1):446 (IF 3.1)
9. Abstract 859: Development of non-smoking lung
cancers by indoor carcinogenic aerosols through epigenetic reprogramming of
lung stem cells: Bioinformatics and artificial intelligence analysis. Anderson,
J,Delgado, M,Lovett, M,Saunders, M,Lake, G,Darko, S,Stiffin, R,Huisso,
A,Sherman, M,Appleton, L,Mihnea, A,Das, S,Algahtani, M M.,Vadapalli, R, Basu,
B et al . Cancer Res (2024) 84 (6_Supplement): 859.
10. Diorganotin(IV) Complexes Containing Hydrazone Ligands as
Prospective Bioactive Agents: Synthesis, Crystal Structure, Spectroscopic
Analysis, Anticancer, and Antimicrobial Activity. Barwa P, Asija S, Deswal Y, Kumar D, Jindal DK, Ghosh S, Basu B et al. Applied Organometallic Chem, 2025.
39(2). e7976 (IF 4.1)
11. Exploring diorganotin(IV) complexes of hydrazone based ligands as
multi- target agents : Synthesis, structural characterization, DFT and in vitro
biological evaluation. Kumar N, Asija S* , Deswal Y,Singh Kirar J, Kumar D,
Jindal D, Basu B, Shukla M. Inorganic Chemistry Communications .2024.
161, 112120 (IF 3.8)
12. Chitosan-insulin nano-formulations as critical
modulators of inflammatory cytokines and Nrf-2 pathway to accelerate burn wound
healing. Sharda D, Ghosh S, P Kaur, Basu B*, Choudhury D*, Discover
Nano. 2023 Dec 12;18(1):154 (IF 6.5)
13. Anti-microbial, anti-oxidant, and anti-breast
cancer properties unraveled in yeast carotenoids
produced via cost-effective fermentation
technique utilizing waste hydrolysate. Sinha S, Das S, Saha B, Paul D*, Basu
B*. Frontiers in Microbiology. 2023. 13. 1088477 (IF 5.2)
14. Synthesis and in vitro anticancer evaluation of 8b-hydroxy-1-(6-substitutedbenzo[d]thiazol-2-yl)-3-(3 substituted
phenyl)-1,8b-dihydroindeno[1,2-c]pyrazol-4(3aH)-ones. Satbir Mor KJ, Khatri M, Punia R, Kumar D, Jindal DK, Basu B, Jakhar
K. Journal of Molecular Structure. 2022. 1269. 133858 (IF 3.8)
15. Is Cancer significant Comorbid Condition in
COVID 19 Infected Patients?
-A Retrospective Analysis Experienced in a Tertiary
Care Center in Eastern India.
Mukherjee K, Dam A,Chakrabarti D, Jatua D, Sengupta S, Dutta R, Majumdar S, Mandal SS, Basu B, Bhattacharjee P, Mukherjee D, Sengupta S, Chakrabarti
J . Annals of Medicine and Surgery, 2022. 81.
104248 (IF 1.7)
16. Bacterioboat—A novel
tool to increase the half-life period of the orally administered drug. Kaur
P, Ghosh S, Bhowmick A, Gadhave K, Datta S, Ghosh A, Garg N, Mahajan RL, Basu B*, Choudhury D* Science Advances.2022.8(10). eabh1419
(IF 13.6)
17. In-vitro antiviral
action of Eupatorium perfoliatum against dengue virus infection: Modulation of
mTOR signaling and autophagy. Sinha M, Chakraborty U, Kool A, Chakravarti M, Das S, Ghosh S, Thakur L,
Khuranna A, Nayak D, Basu B,
Kar S, Ray R*, Das S*. Journal of
Ethnopharmacology, 2022. 282. 114627 (IF
5.4)
18. Ellagic acid-loaded, tween 80-coated, chitosan
nanoparticles as a promising therapeutic approach against breast cancer: In-vitro
and in-vivo study. Kaur H, Ghosh S, Kumar P, Basu B*,
Nagpal K*. Life Sciences, 2022.284. 119927 (IF 6.1)
19.
Pyrrole‐Fused Benzoxazinones/ Quinoxalinones: Molecular Dynamic Simulation, Antiproliferative and Antibacterial Activities. Selvendran S, Das S, Waidha K, Venkatesan S, Balamurali MM, Basu B*Rajendran S*. Chemistry Select, 2021.6(40). 10872-10882 (IF 2.1)
20. Electrospray based fluorescent nanoparticle
synthesis from pyrene butyric acid-functionalized poly (D, L- lactide-coglycolide) polymer for the
efficient delivery of anticancer drug and selfmonitoring its effect inthe drug-resistant breast cancer cells. Chatterjee M, Maity R, Das S, Mahata N, Basu B*, Chanda N*, Materials
Advances. 2020, 1(8),
3033-3048 (IF 5.0)
21. Multi-Component
approach for synthesis
of quinolinyl-1,4-dihydropyridines, evaluation of cytotoxicityagainst
MCF7 and molecular docking studies. Suresh
S, Das S, Waidha K, Maity R, Basu B*, Saravanakumar R* Chemistry
Select. 2020, 5(34), 10501-10510 (IF 2.1)
22. Synthesis, spectral analysis and in vitro
cytotoxicity of diorganotin (IV) complexes derived from indole‐3‐butyric hydrazide. J Devi*, J Yadav, D
Kumar, DK Jindal, Basu B. et al.Applied Organometallic Chemistry.2020, 34(10),
e5815 (IF 3.9)
23.
A novel triazole NMK-T-057 induces autophagic cell death in breast cancer cells
by inhibiting γ- secretase- mediated activation of Notch-signaling. Das A*, Narayanam MK, Paul S, Mukherjee P, Ghosh S,Ghosh
Dastidar D, Chakrabarty S, Ganguli A,
Basu B, Pal M, Chatterji U, Banerjee SK, Karmakar P, Kumar D,Chakrabarti G* .Journal of Biological Chemistry. 2019, 26;294(17):6733-6750 (IF 4.8)
24. Design, synthesis and identification of novel coumaperine derivatives for inhibition of human 5- LOX:Antioxidant,
pseudoperoxidase and docking studies. Muthuraman
S, Sinha S, Vasavi CS, Waidha KM, Basu B, Munussami P, Balamurali MM,
Doble M, S Kumar R*. Bioorg Med
Chem. 2019 ,15;27(4):604-619 (IF
3.5)
25. Novel Nano-insulin Formulation Modulates Cytokine Secretion
and re-epithelialization to Accelerate Diabetic Wound Healing. Kaur P, Sharma AK, Nag D, Das A, Datta S,
Ganguli A, Basu B*,Chowdhury D*.Nanomedicine. 2019 Jan;15(1):47-57
(IF 5.5)
26. Sustainable synthesis of single crystalline sulphur-doped graphene quantum
dots for bioimaging and beyond. Sangam S, Gupta A, Shakeel A, Bhattacharya
R, Sharma AK, Suhag D, Chakrabarti S, Basu
B, Garg SK, Dutta MK, Mukherjee M* Green Chemistry.2018, 20, 4245-4259 (IF 9.8)
27. Dopamine Regulates Angiogenesis in Normal Dermal
Wound Tissues.Shome S, Rana T, Ganguly
S, Basu B, Choudhury S, Sarkar C, Chakroborty D, Dasgupta PS*, Basu S. PLoS One. 2011;6(9):e25215 (IF 3.7)
28. D1 and D2 Dopamine receptor mediated inhibition of
activated normal T cell proliferation is lost in Jurkat Tleukemic cells.Basu B, Sarkar C, Chakroborty D, Ganguly S, Shome S, Dasgupta PS*, Basu S*.Journal of
Biological Chemistry .2010, 285(35): 27026-27032 (IF 4.8)
29.
Dopamine by acting through its D2 receptors inhibits IGF-I induced gastric
cancer cell proliferation by upregulating
Krüppel like factor 4 through down regulation of IGF-IR and AKT
phosphorylation. Ganguly S, Basu B, Shome S, Jadhav T, Roy S, Majumdar J, Dasgupta PS*, Basu S*American Journal
of Pathology, 2010 ,177(6):2701-2707 (IF 6.0)
30.
Stimulation of Dopamine D4 Receptors Induce T Cell Quiescence by Up-Regulating
Kru¨ppel-Like Factor2 Expression
through Inhibition of ERK1/ERK2 Phosphorylation.Sarkar C, Das S, Chakroborty D, Chowdhury UR, Basu B, Dasgupta
PS*, Basu S* Journal of Immunology, 2006, 177: 7525–7529 (IF 4.4)
Review Articles/ Editorials -
1. Obesity and cancer: the possible molecular links Basu B*, Chakroborty D*, Sarkar C* Frontiers in Cell and Developmental Biology.2025 .13. 1542429 , (IF= 4.6)
2. Studies on climate change and its impact on the occupation and health of fisherfolk in West Bengal. Saha S *, Basu B, Dash G. Indian Journal of Environmental Protection, 2024. 44(7): 637
3. Precision Oncology in Era of Genomics and Artificial Intelligence. Das S , Mazumder S , Alam N , Vernekar M , Dam A, Bhowmik AK , Hajra S , Das J , Basu B* ,Journal of Current Oncological Trends, 2024, 1 (1), 22-30
4. The Immunoregulatory Role of Dopamine:An Update. Sarkar C, Basu B, Chakroborty D, Dasgupta PS*, Basu S* Brain, Behavior and Immunity, 2010,
24(4):525-528 (IF 15.1)
5. Catecholamines Regulate Tumor Angiogenesis. Chakroborty D, Sarkar C, Basu B, Dasgupta PS*, Basu S*. Cancer Research, 2009, 69, (9), 2009: 3727-3730 (IF 11.2)
Book Chapters -
1. The Impact of Climate Change on Waterborne Microbial
Diversity and Dysbiosis in Carcinogenesis of Indian Sundarbans Fisherpersons: A
Review. Saha S*, Basu B. Research
Advances in Environment, Geography and Earth Science Vol. 2. April
2024 , 150-170 https://doi.org/10.9734/bpi/raeges/v2/363
2. Implications of Phosphoinositide
3-Kinase (PI3K) Signalling in
Cellular and Molecular Mechanisms of Respiratory Diseases. Basu, B., Ghosh, S., Das, S., Das, A*. (2021). In:
Dua, K., Löbenberg, R., Malheiros Luzo, Â.C., Shukla,
S., Satija, S. (eds) Targeting
Cellular Signalling Pathways
in Lung Diseases. Springer,
Singapore. https://doi.org/10.1007/978-981-33-6827- 9_28
3. Implications of Oxidative Stress and
Epigenetic Drivers in Ovarian Cancer
Progression and Therapy. Das S., Ghosh
S., Bhattacharjee P., Basu B*. (2022)
In: Chakraborti S. (eds) Handbook of Oxidative Stress in Cancer: Therapeutic Aspects.
Springer, Singapore. https://doi.org/10.1007/978-981-16-1247-3_237-1
4. Emerging roles of phospholipases and
lysophosphatidic acid in ovarian
tumorigenesis and their therapeutic targeting. Bhattacharyya P, Mukherjee A, Ghosh S, Basu B*. 2023.In: Chakraborti S. (eds) Phospholipases in Physiologyand Pathology. Volume 3: Role of Phospholipases in Cancer. Elsevier. https://doi.org/10.1016/B978- 0-323-95697-0.00029-7
Mentoring
Mentoring as supervisor (Neuroendocrinology &
Experimental Hematology Lab of CNCI):
Thesis title: Study of autophagy signatures as prognostic
biomarkers and therapeutic targets in Indian breast cancer patients
Thesis title: A study on molecular signatures and
multiregional tumor heterogeneity in ovarian tumors in eastern India and
therapeutic targeting
Thesis title: Study on the role of neuronal regulators in
ovarian cancer progression and chemotherapy induced peripheral neuropathy
Project title: Study on the Role of Microbes and
Neuronal- Immune Regulations in Gastro-Intestinal Cancers and Therapeutic
Implications
Anyone looking for Ph.D/ Post-doctorate /Project Scientist position in our Neuroendocrinology & Experimental Hematology Lab should apply with own fellowship to biswarup.basu@gmail.com



