An Autonomous Body under Ministry of Health and Family Welfare, Govt. of India

Faculty and Staff

Dr. Biswarup Basu Senior Scientific Officer-II

Department: Cancer Research

Education

Biswarup Basu (M.Sc, Ph.D)

Tel. 91-33-24765101(ext-324)

Email id: biswarup.basu@gmail.com ; biswarupbasu@cnci.ac.in  

Linkedin: www.linkedin.com/in/BBasuCNCI

Google Scholar: https://scholar.google.com/citations?user=cIH-rYAAAAAJ&hl=en


Education:

Ph.D (Life Sciences & Biotechnology),Jadavpur University             

M.Sc (Zoology), University of Calcutta, India       

B.Sc (Zoology) ,University of Calcutta, India

1. NET (CSIR-JRF), June 2004,

2. NET (L.S) December 2003

3. GATE 2004(92.88 percentile),

4. SLET 2004

5. CSIR-NEHRU postdoctotorate fellowship, 2010

6. NIH (US) Postdoctorate fellowship ,2011

7. DST-Young Scientist Scheme recipient, 2015

8. DBT-IndiaBiosciences Young Investigators’ Meeting Grant recipient 2023-2024

9. DHR-HRD “Short Term Visiting Fellow in Indian Institutes” awardee 2024

10. Awarded PI projects from DBT, ICMR , WB-DSTBT and CO-PI projects from ICMR,SERB

11. Peer reviewer of Springer-Nature/Elsevier/Wiley journals and funding agencies

10. Life Member of Indian Association for Cancer Research, Indian Science Congress Association, Zoological Society of India, Indian Academy of Neurosciences    

 Chittaranjan National Cancer Institute, Kolkata (SSO-II)                                            2018- Present

 Amity University Uttar Pradesh, Noida (Assistant Professor-III)                                 2015- 2018

 Apeejay Stya University, Haryana (Assistant Professor-II)                                         2013- 2015

 National Cancer Institute,Frederick(NIH),USA ( Postdoc visiting fellow)                    2011-2013


1. Evaluation of autophagy in regulating breast cancer progression

2. Deciphering genomic markers in diagnosis and prognosis of breast and ovarian tumors

3. Mitigation of ovarian patients’ post chemotherapy neurocognitive dysfunction and neuropathy

4. Theranostic drug delivery across blood brain barrier & targeting of brain tumors

5. Development of AI based tools for pathology and radiology guidance

6. Development of bioinspired material based strategies for surgical wound healing and

     chemoradiation impaired skin & bone tissue regeneration

7. Identification of microbial-neuroendocrine-immune axis associated with gastrointestinal cancer 

Full publication link in Google Scholar: https://scholar.google.com/citations?user=cIH-rYAAAAAJ&hl=en

Original Articles -  [* Corresponding Author , IF=Impact Factor]

1. Ultrasound-Mediated Nanocarrier-Based Drug Delivery in Breast Cancer Therapy. Sengupta,

 S., Bhattacharjee, A., Basu, B., Kar, S. and Moulik, S. J Ultrasound Med,2025,45: 735-752  (IF 1.9)

 

2. Design, development, and evaluation of magnetic nanoparticles and docetaxel-loaded nanosystem for brain targeting. Gandhi, H., Kumar, D., Ghosh, S., Basu, B., & Kapoor, D. N. Therapeutic Delivery, 2025, 16(9), 819–834 (IF 2.2)

 

3. Evaluation of anticancer potential of diorganotin(IV) complexes derived from 4-nitro-3-methylbenzhydrazide: Synthesis, spectral and single crystal analysis. Poonia S , Asija S ,  Lal K,  Deswal Y ,  Kumar D ,  Jindal D,  Ghosh S , Basu B et al. Journal of Molecular Structure . 2025,1338, 142361 (IF 3.1)

 

4.  Design, synthesis, anti-breast cancer and in silico studies of substituted triphenyl imidazole-N-alkyl linked indole derivatives Kumar, A., Sengupta, S., Yadav, A. K., Singh, R. P., Sinha, T., Bhattacharjee, P. et al. Future Medicinal Chemistry.  2025,17(14), 1675–1692 (IF 4.76)

 

5. Attenuation of c-Myc expression in breast cancer by hesperidin-mediated stabilization of its promoter proximal G quadruplex region. Choudhury SD, Ghosh S, Kumar P, Bhardwaj A, Singh K, Singh A, Kumar A, Basu B, Giri R, Choudhury D. Int J Biol Macromol. 2025 May;309(Pt 4):143000. (IF 7.7)

 

6. Anti-proliferative and Apoptotic Efficacy of Nano-PLGA encapsulated Quercetin Molecules by down- regulation of Akt in K-ras mutated NSCLC cell lines, A549 and H460. Mukherjee A, Ghosh S, Ganguli S, Basu B. J Biochem Mol Toxicol. 2025 Apr;39(4):e70240. (IF 3.9)

 

7. Editorial: Obesity and cancer: the possible molecular links. Basu B*, Chakroborty D, Sarkar C. Front Cell Dev Biol. 2025 Feb 11;13:1542429 (IF 4.5)

 

8. Epidermal Growth Factor Receptor (EGFR) and SMAD4 negatively correlated in the progression of gallbladder cancer in Eastern Indian patients. Choudhury S, Ghosh S, Chakraborty P, Pal S, Ghosh K, Saha S, Midha J, Sankar V, Mohata A, Chattopadhyay BK, Ghosh S, Das S, Basu B, Sikdar N. BMC Gastroenterol. 2024 Dec 3;24(1):446 (IF 3.1)

 

9. Abstract 859: Development of non-smoking lung cancers by indoor carcinogenic aerosols through epigenetic reprogramming of lung stem cells: Bioinformatics and artificial intelligence analysis. Anderson, J,Delgado, M,Lovett, M,Saunders, M,Lake, G,Darko, S,Stiffin, R,Huisso, A,Sherman, M,Appleton, L,Mihnea, A,Das, S,Algahtani, M M.,Vadapalli, R, Basu, B et al . Cancer Res (2024) 84 (6_Supplement): 859.

10. Diorganotin(IV) Complexes Containing Hydrazone Ligands as Prospective Bioactive Agents: Synthesis, Crystal Structure, Spectroscopic Analysis, Anticancer, and Antimicrobial Activity. Barwa P, Asija S, Deswal Y, Kumar D, Jindal DK, Ghosh S, Basu B et al. Applied Organometallic Chem, 2025. 39(2). e7976 (IF 4.1)

11. Exploring diorganotin(IV) complexes of hydrazone based ligands as multi- target agents : Synthesis, structural characterization, DFT and in vitro biological evaluation. Kumar N, Asija S* , Deswal Y,Singh Kirar J, Kumar D, Jindal D, Basu B, Shukla M. Inorganic Chemistry Communications .2024. 161, 112120 (IF 3.8)

 

12. Chitosan-insulin nano-formulations as critical modulators of inflammatory cytokines and Nrf-2 pathway to accelerate burn wound healing. Sharda D, Ghosh S, P Kaur, Basu B*, Choudhury D*, Discover Nano. 2023 Dec 12;18(1):154 (IF 6.5)

 

13. Anti-microbial, anti-oxidant, and anti-breast cancer properties unraveled in yeast carotenoids

 produced via cost-effective fermentation technique utilizing waste hydrolysate. Sinha S, Das S, Saha B, Paul D*, Basu B*. Frontiers in Microbiology. 2023. 13. 1088477 (IF 5.2)

 

14. Synthesis and in vitro anticancer evaluation of 8b-hydroxy-1-(6-substitutedbenzo[d]thiazol-2-yl)-3-(3 substituted phenyl)-1,8b-dihydroindeno[1,2-c]pyrazol-4(3aH)-ones. Satbir Mor KJ, Khatri M, Punia R, Kumar D, Jindal DK, Basu B, Jakhar K. Journal of Molecular Structure. 2022. 1269. 133858 (IF 3.8)

15. Is Cancer significant Comorbid Condition in COVID 19 Infected Patients? -A Retrospective Analysis Experienced in a Tertiary Care Center in Eastern India. Mukherjee K, Dam A,Chakrabarti D, Jatua D, Sengupta S, Dutta R, Majumdar S, Mandal SS, Basu B, Bhattacharjee P, Mukherjee D, Sengupta S, Chakrabarti J . Annals of Medicine and Surgery, 2022. 81. 104248 (IF 1.7)

 

16. Bacterioboat—A novel tool to increase the half-life period of the orally administered drug. Kaur P, Ghosh S, Bhowmick A, Gadhave K, Datta S, Ghosh A, Garg N, Mahajan RL, Basu B*, Choudhury D* Science Advances.2022.8(10). eabh1419 (IF 13.6)

 

17. In-vitro antiviral action of Eupatorium perfoliatum against dengue virus infection: Modulation of mTOR signaling and autophagy. Sinha M, Chakraborty U, Kool A, Chakravarti M, Das S, Ghosh S, Thakur L, Khuranna A, Nayak D, Basu B, Kar S, Ray R*, Das S*. Journal of Ethnopharmacology, 2022. 282. 114627 (IF 5.4)

 

18. Ellagic acid-loaded, tween 80-coated, chitosan nanoparticles as a promising therapeutic approach against breast cancer: In-vitro and in-vivo study. Kaur H, Ghosh S, Kumar P, Basu B*, Nagpal K*. Life Sciences, 2022.284. 119927 (IF 6.1)

 

19. Pyrrole‐Fused Benzoxazinones/ Quinoxalinones: Molecular Dynamic Simulation, Antiproliferative and Antibacterial Activities. Selvendran S, Das S, Waidha K, Venkatesan S, Balamurali MM, Basu B*Rajendran S*. Chemistry Select, 2021.6(40). 10872-10882 (IF 2.1)

 

20. Electrospray based fluorescent nanoparticle synthesis from pyrene butyric acid-functionalized poly (D, L- lactide-coglycolide) polymer for the efficient delivery of anticancer drug and selfmonitoring its effect inthe drug-resistant breast cancer cells. Chatterjee M, Maity R, Das S, Mahata N, Basu B*, Chanda N*, Materials Advances. 2020, 1(8), 3033-3048 (IF 5.0)

 

21. Multi-Component approach for synthesis of quinolinyl-1,4-dihydropyridines, evaluation of cytotoxicityagainst MCF7 and molecular docking studies. Suresh S, Das S, Waidha K, Maity R, Basu B*, Saravanakumar R* Chemistry Select. 2020, 5(34), 10501-10510 (IF 2.1)

 

22. Synthesis, spectral analysis and in vitro cytotoxicity of diorganotin (IV) complexes derived from indole‐3‐butyric hydrazide. J Devi*, J Yadav, D Kumar, DK Jindal, Basu B. et al.Applied Organometallic Chemistry.2020, 34(10), e5815 (IF 3.9)

 

23. A novel triazole NMK-T-057 induces autophagic cell death in breast cancer cells by inhibiting γ- secretase- mediated activation of Notch-signaling. Das A*, Narayanam MK, Paul S, Mukherjee P, Ghosh S,Ghosh Dastidar D, Chakrabarty S, Ganguli A, Basu B, Pal M, Chatterji U, Banerjee SK, Karmakar P, Kumar D,Chakrabarti G* .Journal of Biological Chemistry. 2019, 26;294(17):6733-6750 (IF 4.8)

 

24. Design, synthesis and identification of novel coumaperine derivatives for inhibition of human 5- LOX:Antioxidant, pseudoperoxidase and docking studies. Muthuraman S, Sinha S, Vasavi CS, Waidha KM, Basu B, Munussami P, Balamurali MM, Doble M, S Kumar R*. Bioorg Med Chem. 2019 ,15;27(4):604-619 (IF 3.5)

 

25. Novel Nano-insulin Formulation Modulates Cytokine Secretion and re-epithelialization to Accelerate Diabetic Wound Healing. Kaur P, Sharma AK, Nag D, Das A, Datta S, Ganguli A, Basu B*,Chowdhury D*.Nanomedicine. 2019 Jan;15(1):47-57 (IF 5.5)

 

26. Sustainable synthesis of single crystalline sulphur-doped graphene quantum dots for bioimaging and beyond. Sangam S, Gupta A, Shakeel A, Bhattacharya R, Sharma AK, Suhag D, Chakrabarti S, Basu B, Garg SK, Dutta MK, Mukherjee M* Green Chemistry.2018, 20, 4245-4259 (IF 9.8)

 

27. Dopamine Regulates Angiogenesis in Normal Dermal Wound Tissues.Shome S, Rana T, Ganguly S, Basu B, Choudhury S, Sarkar C, Chakroborty D, Dasgupta PS*, Basu S. PLoS One. 2011;6(9):e25215 (IF 3.7)

 

28. D1 and D2 Dopamine receptor mediated inhibition of activated normal T cell proliferation is lost in Jurkat Tleukemic cells.Basu B, Sarkar C, Chakroborty D, Ganguly S, Shome S, Dasgupta PS*, Basu S*.Journal of Biological Chemistry .2010, 285(35): 27026-27032 (IF 4.8)

 

29. Dopamine by acting through its D2 receptors inhibits IGF-I induced gastric cancer cell proliferation by upregulating Krüppel like factor 4 through down regulation of IGF-IR and AKT phosphorylation. Ganguly S, Basu B, Shome S, Jadhav T, Roy S, Majumdar J, Dasgupta PS*, Basu S*American Journal of Pathology, 2010 ,177(6):2701-2707 (IF 6.0)

 

30. Stimulation of Dopamine D4 Receptors Induce T Cell Quiescence by Up-Regulating Kru¨ppel-Like Factor2 Expression through Inhibition of ERK1/ERK2 Phosphorylation.Sarkar C, Das S, Chakroborty D, Chowdhury UR, Basu B, Dasgupta PS*, Basu S* Journal of Immunology, 2006, 177: 7525–7529 (IF 4.4)


Review Articles/ Editorials -


1. Obesity and cancer: the possible molecular links Basu B*, Chakroborty D*, Sarkar C*  Frontiers in Cell and Developmental Biology.2025 .13. 1542429 , (IF= 4.6)

2. Studies on climate change and its impact on the occupation and health of fisherfolk in West Bengal. Saha S *, Basu B, Dash G. Indian Journal of  Environmental Protection, 2024. 44(7): 637

3. Precision Oncology in Era of Genomics and Artificial Intelligence. Das S , Mazumder S , Alam N , Vernekar M , Dam A, Bhowmik AK , Hajra S , Das J , Basu B* ,Journal of Current Oncological Trends, 2024, 1 (1), 22-30

4. The Immunoregulatory Role of Dopamine:An Update. Sarkar C, Basu B, Chakroborty D, Dasgupta PS*, Basu S* Brain, Behavior and Immunity, 2010,

24(4):525-528 (IF 15.1)

5. Catecholamines Regulate Tumor Angiogenesis. Chakroborty D, Sarkar C, Basu B, Dasgupta PS*, Basu S*. Cancer Research, 2009, 69, (9), 2009: 3727-3730 (IF 11.2)


Book Chapters -


1. The Impact of Climate Change on Waterborne Microbial Diversity and Dysbiosis in Carcinogenesis of Indian Sundarbans Fisherpersons: A Review. Saha  S*, Basu B. Research Advances in Environment, Geography and Earth Science Vol. 2. April 2024 , 150-170 https://doi.org/10.9734/bpi/raeges/v2/363

 

2. Implications of Phosphoinositide 3-Kinase (PI3K) Signalling in Cellular and Molecular Mechanisms of Respiratory Diseases. Basu, B., Ghosh, S., Das, S., Das, A*. (2021). In: Dua, K., Löbenberg, R., Malheiros Luzo, Â.C., Shukla, S., Satija, S. (eds) Targeting Cellular Signalling Pathways in Lung Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-33-6827- 9_28

 

3. Implications of Oxidative Stress and Epigenetic Drivers in Ovarian Cancer Progression and Therapy. Das S., Ghosh S., Bhattacharjee P., Basu B*. (2022) In: Chakraborti S. (eds) Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. Springer, Singapore. https://doi.org/10.1007/978-981-16-1247-3_237-1

 

4. Emerging roles of phospholipases and lysophosphatidic acid in ovarian tumorigenesis and their therapeutic targeting. Bhattacharyya P, Mukherjee A, Ghosh S, Basu B*. 2023.In: Chakraborti S. (eds) Phospholipases in Physiologyand Pathology. Volume 3: Role of Phospholipases in Cancer. Elsevier. https://doi.org/10.1016/B978- 0-323-95697-0.00029-7

 

Mentoring as supervisor (Neuroendocrinology & Experimental Hematology Lab of CNCI):

 1. Dr Arijit Bhowmik, Project Scientist-II (under DBT funded project)

 2. Mr. Sandip Ghosh, UGC-SRF

Thesis title: Study of autophagy signatures as prognostic biomarkers and therapeutic targets in Indian breast cancer patients

 3. Mr. Souvik Das, UGC-SRF

Thesis title: A study on molecular signatures and multiregional tumor heterogeneity in ovarian tumors in eastern India and therapeutic targeting

 4. Ms Pratiti Bhattacharjee, CSIR-SRF,

Thesis title: Study on the role of neuronal regulators in ovarian cancer progression and chemotherapy induced peripheral neuropathy

 5. Ms. Vijna Danish, DBT-BET SRF

Project title: Study on the Role of Microbes and Neuronal- Immune Regulations in Gastro-Intestinal Cancers and Therapeutic Implications

 

Anyone looking for Ph.D/ Post-doctorate /Project Scientist position in our Neuroendocrinology & Experimental Hematology Lab should apply with own fellowship to biswarup.basu@gmail.com