Department Name:

Environmental Carcinogenesis And Toxicology

H.O.D Name:

Dr. Madhumita Roy,Senior Scientific Officer(Assistant Director Grade)


Phone:91-33-2476-5101 (ext-317) Fax No: 91-33-2475-7606 E-mail- mitacnci@yahoo.co.in ; mitacnci@gmail.com & E-mail- sutapa_c_in@yahoo.com


Objective 1: To study the modulation of tumor markers by dietary phytochemicals sensitize cancer cells towards chemotherapeutic drugs Objective 2: To elucidate the effect of green tea polyphenol, EGCG on Lipid Rafts and Caveolae in human breast cancer cells MCF-7 and MDA-MB-231cells. Objective 3: Enhancement of imatinib sensitivity in drug resistant chronic myeloid leukemia cells K562 by curcumin via modulation of various signaling mechanism. Objective 4: Prevention of 4NQO induced oral cell carcinoma in animal model by black tea by modulation of different protein tyrosine kinases and their phosphorylation status. Objective 5: Determination of the constitutive expression of Aurora kinases A and B (AUR A and AUR B) in breast adenocarcinoma cell line MCF-7, highly metastatic breast cancer cell line MDA-MB-231 (triple negative). To follow the modulation of the same by curcumin. Objective 6: Synchronization of estrus cycle and determination of exfoliated cell morphology in female Swiss albino mice. Objective 7: Development of arsenic induced skin squamous cell carcinoma in Swiss albino mice and its prevention by black tea. Objective 8: Comparative study of population chronically exposed to arsenic in two different demographic regions of Eastern India: Identification of responsible genes and susceptible population

Lab Member:

Dr Sutapa Mukherjee, Senior Scientific Officer, Ms Apurba Mukherjee, SRF Mr Souvick Biswas, JRF Ms Elizabeth Mahapatro, JRF Mr Archismaan Ghosh, JRF Mr Sunit Roy, Contingent worker

Brief description of the ongoing research work:


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